{"id":1187,"date":"2026-01-25T15:19:09","date_gmt":"2026-01-25T21:19:09","guid":{"rendered":"https:\/\/zogen.local\/?p=1187"},"modified":"2026-01-25T15:19:09","modified_gmt":"2026-01-25T21:19:09","slug":"smoking-shrinks-the-brain","status":"publish","type":"post","link":"https:\/\/zogen.mx\/en\/fumar-encoge-al-cerebro\/","title":{"rendered":"Does smoking shrink the brain?"},"content":{"rendered":"<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/zogen.local\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-1024x576.png\" alt=\"\" class=\"wp-image-1188\" srcset=\"https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-1024x576.png 1024w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-300x169.png 300w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-768x432.png 768w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-1536x864.png 1536w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-640x360.png 640w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-400x225.png 400w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-367x206.png 367w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10-600x338.png 600w, https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10.png 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>In today&#039;s article we will talk about one of the side effects that smoking has on our body. Among the large number of negative effects that it causes in our body, recently there has been much talk about whether smoking shrinks the brain. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Let&#039;s talk about the data<\/h2>\n\n\n\n<p>In the ongoing effort to understand the complex health effects of smoking, a new study based on UK Biobank data sheds light on the relationship between daily smoking and brain volume. Amid the debate over whether smoking causes a decrease in brain volume or whether brain volume is a risk factor for smoking, we explored these links using methods that assess the directionality of the association.<\/p>\n\n\n\n<p> The study was conducted with the participation of 32,094 individuals of European ancestry, using Bradford Hill criteria, commonly employed to understand causal relationships in epidemiological studies. Furthermore, mediation analysis was used to delve deeper into the underlying mechanisms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Results<\/h2>\n\n\n\n<p>So, does smoking shrink the brain? The findings reveal that a history of daily smoking is significantly associated with a decrease in brain volume, and this association intensifies in cases of heavy smoking. The most pronounced relationship was observed between total gray matter volume and a history of daily smoking, with a remarkable effect size (\u22122964 mm3, p = 2.04 \u00d7 10\u221216). <\/p>\n\n\n\n<p>Furthermore, a dose-response relationship was identified, where a higher number of pack-years smoked was associated with a greater decrease in brain volume. The polygenic risk score for smoking initiation showed a strong association with a history of daily smoking, while its association with total gray matter volume was more modest.<\/p>\n\n\n\n<p>This study reinforces the direct link between daily smoking and a decrease in total brain volume; indeed, smoking shrinks the brain. The results not only provide valuable information about the effects of tobacco on brain health, but also open the door to a deeper understanding of the genetic mechanisms underlying this phenomenon. This is another step toward elucidating the complex links between smoking and brain health.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><a href=\"https:\/\/zogen.local\/product\/health-check\/\">Discover your genetic risk with Health Check: Beyond conventional genetic testing<\/a><\/strong><\/h2>\n\n\n\n<p>At Zogen, we understand that every individual is unique, and their health is a complex interplay of genetic and environmental factors. The Health Check genetic test stands as a pioneering tool, not only revealing your genetic predispositions but also offering a clear view of how your lifestyle, such as smoking, might interact with your genetic code.<\/p>\n\n\n\n<p><strong>Tobacco Addiction:<\/strong> Health Check not only tells you if you&#039;re genetically predisposed to tobacco addiction, but goes further, uncovering the specific genetic markers associated with nicotine susceptibility. This not only gives you a deeper understanding of your relationship with tobacco, but also empowers you to make informed decisions about your smoking habits.<\/p>\n\n\n\n<p><strong>Risk of Cardiovascular Disease: A Preventive Approach:<\/strong> The link between smoking and cardiovascular disease is well-established, but Health Check personalizes this information based on your genetic profile. By identifying genetic markers associated with heart disease, the test empowers you with insights that go beyond generic warnings. You can understand how your genetic predisposition and lifestyle choices intertwine, enabling you to take concrete preventative measures.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How it Works:<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Simple DNA Sample:<\/strong> Health Check requires a saliva sample. No needles or complicated procedures required; a simple saliva sample is all it takes to unlock the secrets of your genetics.<\/li>\n\n\n\n<li><strong>Precise Analysis:<\/strong> Our team of experts analyzes your DNA sample using cutting-edge technology. Health Check evaluates a wide range of genetic markers, from disease predisposition to specific characteristics of your response to tobacco.<\/li>\n\n\n\n<li><strong>Personalized Information:<\/strong> Once the analysis is complete, you will receive a detailed and easy-to-understand report. This report will include your genetic risks associated with smoking and cardiovascular disease, providing you with a comprehensive overview.<\/li>\n<\/ol>\n\n\n\n<p><strong>Take Control of Your Health:<\/strong> The Health Check test doesn&#039;t just inform you; it gives you control. With this information at hand, you can precisely tailor your lifestyle, making choices that align with your unique biology. From smoking cessation strategies to personalized approaches to cardiovascular health, zogen supports you every step of the way.<\/p>\n\n\n\n<p>Fuente: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2667174323001362?via%3Dihub<\/p>","protected":false},"excerpt":{"rendered":"<p>En el articulo de hoy hablaremos sobre uno de los efectos secundarios que tiene el tabaquismo en nuestro organismo, dentro de la gran cantidad de efectos negativos que este provoca en nuestro cuerpo, a recientes fechas se ha hablado mucho sobre si fumar encoge al cerebro. Hablemos de los datos En el continuo esfuerzo por [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":1188,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[],"tags":[],"class_list":["post-1187","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u00bfFumar encoge al cerebro? - zogen<\/title>\n<meta name=\"description\" content=\"\u00bfFumar encoge al cerebro? Los hallazgos revelan que el tabaquismo est\u00e1 significativamente asociado con una disminuci\u00f3n del volumen cerebral.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zogen.mx\/en\/smoking-shrinks-the-brain\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00bfFumar encoge al cerebro? - zogen\" \/>\n<meta property=\"og:description\" content=\"\u00bfFumar encoge al cerebro? Los hallazgos revelan que el tabaquismo est\u00e1 significativamente asociado con una disminuci\u00f3n del volumen cerebral.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/zogen.mx\/en\/smoking-shrinks-the-brain\/\" \/>\n<meta property=\"og:site_name\" content=\"zogen\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/zogenmx\" \/>\n<meta property=\"article:published_time\" content=\"2026-01-25T21:19:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/zogen.mx\/wp-content\/uploads\/2023\/12\/Gracias-por-tu-compra-10.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"marketing zogen\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"marketing zogen\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/\"},\"author\":{\"name\":\"marketing zogen\",\"@id\":\"https:\\\/\\\/zogen.mx\\\/#\\\/schema\\\/person\\\/d00aafe7bbe11fd011641cc1be4c665f\"},\"headline\":\"\u00bfFumar encoge al cerebro?\",\"datePublished\":\"2026-01-25T21:19:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/\"},\"wordCount\":834,\"publisher\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/zogen.mx\\\/wp-content\\\/uploads\\\/2023\\\/12\\\/Gracias-por-tu-compra-10.png\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/\",\"url\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/\",\"name\":\"\u00bfFumar encoge al cerebro? - zogen\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/zogen.mx\\\/fumar-encoge-al-cerebro\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/zogen.mx\\\/wp-content\\\/uploads\\\/2023\\\/12\\\/Gracias-por-tu-compra-10.png\",\"datePublished\":\"2026-01-25T21:19:09+00:00\",\"description\":\"\u00bfFumar encoge al cerebro? 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